norfloxacin, Noroxin (cont.)

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Medical and Pharmacy Editor:

PRESCRIPTION: Yes

GENERIC AVAILABLE: Not in US, in Canada

PREPARATIONS: Tablets: 400 mg

STORAGE: Store norfloxacin tablets between temperatures of 15 C - 30 C (59 F - 86 F), in a tightly closed container.

PRESCRIBED FOR: Norfloxacin is used for treatment of susceptible organisms causing urinary tract infections, prostatitis, and gonorrhea.

DOSING:

  • Uncomplicated urinary tract infection: Take 1 tablet (400 mg) by mouth every 12 hours for 3 days
  • Complicated urinary tract infection: Take 1 tablet (400 mg) by mouth every 12 hours for 10 to 21 days.
  • For infections caused by E. coli, K. pneumoniae, or P. mirabilis only. Take 1 tablet (400 mg) by mouth every 12 hours for 7 to 10 days, for infections caused by any other bacteria.
  • Prostatitis: Take 1 tablet (400 mg) by mouth every 12 hours for 28 to 42 days.
  • Gonorrhea: Take 2 tablets (800 mg) by mouth as one single dose.

Safe and effective use of norfloxacin is not established in patients under the age of 18 years.

Note that some organisms are resistant to norfloxacin; organisms should be tested for susceptibility to this drug.

DRUG INTERACTIONS: Norfloxacin should be used with caution with medications like caffeine, clozapine (Clozaril), ropinorole (Requip), cyclosporine (Neoral, Sandimmune, Gengraf), theophylline (Theo-24), and tizanidine (Zanaflex) because norfloxacin can slow down breakdown of these medications in and increase their levels in the body.

Medically Reviewed by a Doctor on 10/24/2014


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