norethindrone (Aygestin, Norlutate) (cont.)

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Secondary amenorrhea and abnormal uterine bleeding: Take 2.5 to 10 mg by mouth once daily for 5 to 10 days, during second half of the menstrual cycle.

Endometriosis: Initially, take 5 mg by mouth once daily for first 2 weeks, and then increase dose by 2.5 mg per day every 2 weeks until 15 mg per day of norethindrone is reached. Treatment is continued for 6 to 9 months.

DRUG INTERACTIONS: No drug-drug interactions have been conducted and established with norethindrone.

PREGNANCY: Norethindrone is not recommended for pregnant mothers under any circumstances. Norethindrone may cause birth defects.

NURSING MOTHERS: Norethindrone may enter in breast milk in trace amounts. It should be used with extreme caution in nursing mothers.

SIDE EFFECTS: Side effects of norethindrone are edema, nausea, breast tenderness, irregular menstrual cycle, breakthrough bleeding, spotting, weight change, and headache. Deep vein thrombosis and depression may also occur.

REFERENCE: FDA Prescribing Information

Medically Reviewed by a Doctor on 10/10/2014

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