GENERIC NAME: Norethindrone acetate
BRAND NAME: Aygestin, Norlutate
DRUG CLASS AND MECHANISM: Norethindrone is a man-made progestin used for treating abnormal uterine bleeding and related condtions (such as amenorrhea and endometriosis). Progestins are steroid hormones that have the same effect as progesterone. Norethindrone works by stopping gonadotropin production from the pituitary gland, leading to prevention of ovulation in females. The FDA approved norethindrone in April, 1982.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 5 mg tablets
STORAGE: Store norethindrone tablets between temperatures of 20 C to 25 C (68 F to 77 F).
PRESCRIBED FOR: Norethindrone is used for the treatment of secondary amenorrhea, abnormal uterine bleeding, and endometriosis due to hormone imbalance.
Secondary amenorrhea and abnormal uterine bleeding: Take 2.5 to 10 mg by mouth once daily for 5 to 10 days, during second half of the menstrual cycle.
Endometriosis: Initially, take 5 mg by mouth once daily for first 2 weeks, and then increase dose by 2.5 mg per day every 2 weeks until 15 mg per day of norethindrone is reached. Treatment is continued for 6 to 9 months.
DRUG INTERACTIONS: No drug-drug interactions have been conducted and established with norethindrone.
PREGNANCY: Norethindrone is not recommended for pregnant mothers under any circumstances. Norethindrone may cause birth defects.
NURSING MOTHERS: Norethindrone may enter in breast milk in trace amounts. It should be used with extreme caution in nursing mothers.
Quick GuideEndometriosis: Symptoms, Signs, Treatment
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.