Nonsteroidal Anti-inflammatory Drugs (NSAIDS) and Ulcers

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Pharmacy Author:

Omudhome Ogbru, PharmD

Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

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Medical and Pharmacy Editor:

Jay W. Marks, MD

Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed medications for the inflammation of arthritis and other body tissues, such as in tendinitis and bursitis. The are also used for minor aches and pain.

Examples of NSAIDs include:

• aspirin,
• indomethacin (Indocin),
• ibuprofen (Motrin),
• naproxen (Naprosyn),
• piroxicam (Feldene),
• nabumetone (Relafen), and
• Celecoxib (Celebrex).

NSAIDs are available by prescription or without a prescription (over-the-counter). They are also ingredients in many over the counter medications used for colds and minor aches and pain. They are administered orally as capsules, tablets, liquids, or by injection ketorolac (Toradol). Although not included in this review, NSAIDs are also used as eye drops for eye inflammation (for example, ketorolac tromethamine [Acular]).

NSAIDs are taken regularly by approximately 33 million Americans and over 30 billion doses of NSAIDs are consumed annually in the United States.