nizatidine, Axid, Axid AR (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
DRUG INTERACTIONS: Nizatidine, like other drugs that reduce stomach acid, may interfere with the absorption of drugs that require acid for adequate absorption. Examples include iron salts (for example iron sulphate), itraconazole (Sporanox), and ketoconazole (Nizoral, Extina, Xolegel, Kuric), atazanavir (Reyataz), dasatinib (Sprycel), indinavir (Crixivan), and dapsone. Conversely, it may increase levels of nimodipine (Nimotop) and nisoldipine (Sular) due to reduced stomach acidity.
PREGNANCY: There are no adequate studies in pregnant women. Available evidence suggests that there is little risk when used during pregnancy.
NURSING MOTHERS: Nizatidine is secreted into human breast milk and may pose a potential risk to the infant.
SIDE EFFECTS: Common side effects include constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, vomiting, dizziness, confusion, depression and agitation. Serious but rare side effects include anemia, and a reduction in white blood cells or platelets. Hepatitis also has been reported.
Reference: FDA Prescribing Information
Last Editorial Review: 7/25/2012
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