nitazoxanide, Alinia

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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DOSING:

The recommended dose for treating diarrhea caused by Giardia lamblia or Cryptosporidium parvum in children 1 to 11 years of age is 5 to 10 ml every 12 hours with food for 3 days. Patients 12 years of age or older are treated with 500 mg (1 tablet) or 25 ml every 12 hours with food for 3 days.

PREPARATIONS: Tablet: 500 mg; Oral suspension: 100 mg/5 ml

DRUG INTERACTIONS: There are no significant drug interactions listed for nitazoxanide.

PREGNANCY AND BREASTFEEDING SAFETY:

Nitazoxanide has not been adequately evaluated in pregnant women.

It is not known whether nitazoxanide is excreted in human milk.

STORAGE: Nitazoxanide should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

DRUG CLASS AND MECHANISM:

  • Nitazoxanide is an oral medication that prevents growth of Giardia lamblia and Cryptosporidium parvum.
  • Giardia lamblia and Cryptosporidium parvum are protozoans that cause diarrhea.
  • Nitazoxanide works by interfering with the conversion of chemicals to energy in protozoal cells.
  • The FDA approved nitazoxanide on July 21, 2004.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 1/13/2016
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