The recommended dose for treating diarrhea caused by Giardia lamblia or Cryptosporidium parvum in children 1 to 11 years of age is 5 to 10 ml every 12 hours with food for 3 days. Patients 12 years of age or older are treated with 500 mg (1 tablet) or 25 ml every 12 hours with food for 3 days.
PREPARATIONS: Tablet: 500 mg; Oral suspension: 100 mg/5 ml
DRUG INTERACTIONS: There are no significant drug interactions listed for nitazoxanide.
PREGNANCY AND BREASTFEEDING SAFETY:
Nitazoxanide has not been adequately evaluated in pregnant women.
It is not known whether nitazoxanide is excreted in human milk.
STORAGE: Nitazoxanide should be stored at room temperature, 15 C to 30 C (59 F to 86 F).
DRUG CLASS AND MECHANISM:
- Nitazoxanide is an oral medication that prevents growth of Giardia lamblia and Cryptosporidium parvum.
- Giardia lamblia and Cryptosporidium parvum are protozoans that cause diarrhea.
- Nitazoxanide works by interfering with the conversion of chemicals to energy in protozoal cells.
- The FDA approved nitazoxanide on July 21, 2004.
Reference: FDA Prescribing Information
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