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- What is nisoldipine, and how does it work (mechanism of action)?
- What brand names are available for nisoldipine?
- Is nisoldipine available as a generic drug?
- Do I need a prescription for nisoldipine?
- What are the side effects of nisoldipine?
- What is the dosage for nisoldipine?
- Which drugs or supplements interact with nisoldipine?
- Is nisoldipine safe to take if I'm pregnant or breastfeeding?
- What else should I know about nisoldipine?
What is nisoldipine, and how does it work (mechanism of action)?
Nisoldipine is an oral calcium channel blocker (CCB) of the dihydropyridine (DHP) class that is used to treat high blood pressure. Other calcium channel blockers in the DHP class include nifedipine (Procardia, Adalat), amlodipine (Norvasc), felodipine (Plendil), nicardipine (Cardene), and isradipine (Dynacirc). Calcium channel blockers prevent calcium from entering certain types of muscle cells. Since the muscle cells need calcium to contract, CCBs prevent the cells from contracting, that is, they cause the muscle cells to relax. Nisoldipine selectively relaxes the muscles of small arteries causing the arteries to dilate but has little or no effect on muscles of veins or the heart. Dilation of arteries reduces blood pressure. Nisoldipine was approved by the FDA in February of 1995.
What brand names are available for nisoldipine?
Is nisoldipine available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for nisoldipine?
What are the side effects of nisoldipine?
The most common side effects of nisoldipine are:
- Peripheral edema (swollen ankles and feet),
- Hypersensitivity reactions,
- worsening of chest pain,
- low blood pressure, and
- heart attacks
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