nifedipine, Adalat (discontinued brand), Procardia, Afeditab, Nifediac (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Less common side effects include:

Uncommon side effects include:

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Capsules: 10 and 20 mg. Tablets: 30, 60, and 90 mg

STORAGE: Tablets should be stored at room temperature 15 C to 25 C (59 F to 77 F). They should be protected from light, moisture, and humidity.

DOSING:

  • The usual dose for nifedipine capsules for treating angina is 10 to 20 mg three times daily. Up to 20 to 30 mg every 6-8 hours daily may be required. The dose should not exceed 180 mg daily. For extended release tablets, the usual dose is 30 or 60 mg once daily. The maximum dose is 120 mg daily.
  • Hypertension is treated with 30-60 mg daily using extended release tablets. The maximum dose is 90 mg/day (Adalat CC) or 120 mg/day (Procardia XL).
  • Nifedipine can be taken with or without food.
  • The tablets and capsules should be swallowed whole and not bitten or cut in half.

DRUG INTERACTIONS: In rare instances, congestive heart failure has been associated with nifedipine, usually in patients already on a beta blocker, for example, propranolol (Inderal), metoprolol (Lopressor), etc. Excessive lowering of blood pressure (hypotension) during initiation of nifedipine treatment can occur, especially in patients already taking another blood pressure lowering drug.

Generally, nifedipine is avoided in children.

Nifedipine decreases the elimination of digoxin (Lanoxin) by the kidneys which can increase digoxin blood levels in the blood and give rise to digoxin toxicity. It is important, therefore, to monitor blood levels of digoxin in order to avoid toxicity.

Medically Reviewed by a Doctor on 12/17/2014


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