Nicorette Gum (nicotine polacrilex, Nicorelief, Nicorette, Thrive)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

DOSAGE:

  • Light smokers (less than 25 cigarettes per day): Use 1 piece of 2 mg gum every 1 to 2 hours for weeks 1 to 6; then use 1 piece of 2 mg every 2 to 4 hours for weeks 7 to 9; then use 1 piece of 2 mg gum every 4 to 8 hours for weeks 10 to 12.
  • Heavy smokers (more than 25 cigarettes per day): Use 1 piece of 4 mg gum every 1 to 2 hours for weeks 1 to 6; then use 1 piece of 4 mg every 2 to 4 hours for weeks 7 to 9; then use 1 piece of 4 mg gum every 4 to 8 hours for weeks 10 to 12.

Individuals should not use more than 24 pieces of nicotine gum per day. It is not recommended to eat or drink 15 minutes before or while chewing the gum. It is not recommended to use nicotine gum for more than 12 weeks.

DRUG INTERACTIONS:

  • Nicotine gums may cause abnormal heart rate and rhythm in patients maintained on anti-arrhythmia medications.
  • Patients with high blood pressure (hypertension), insulin-dependent diabetes, or coronary artery disease should use nicotine gum with caution or consult a doctor before use.

PREGNANCY AND BREASTFEEDING SAFETY:

  • There are no adequate studies of nicotine to determine safe and effective use in pregnant women.
  • It is not known if nicotine enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

PREPARATIONS: Nicotine gum is available in 2 and 4 mg strengths.

STORAGE: Nicotine gums should be stored at room temperature between 20 C and 25 C (68 F and 77 F).

How does nicotine polacrilex (Nicorrette Gum, Nicorelief, Nicorette, Thrive) work?

  • Nicotine gum is a smoking cessation agent. Nicotine gums works by releasing nicotine which is absorbed into the body and binds to nicotine receptors, reducing nicotine craving and withdrawal symptoms associated with smoking cessation.
  • The FDA approved nicotine gum in January, 1984.

REFERENCES:

FDA Prescribing Information.

Medically Reviewed by a Doctor on 9/30/2016

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