nicotine polacrilex (Nicorette Gum, Nicorelief, Nicorette, Thrive)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: nicotine polacrilex

BRAND NAME: Nicorette Gum, Nicorelief, Nicorette, Thrive

DRUG CLASS AND MECHANISM: Nicotine gum is a smoking cessation agent. Nicotine gums works by releasing nicotine which is absorbed into the body and binds to nicotine receptors, reducing nicotine craving and withdrawal symptoms associated with smoking cessation. The FDA approved nicotine gum in January, 1984.

PRESCRIBED FOR: Nicotine gum is used to control nicotine withdrawal symptoms and cravings associated with smoking cessation.

SIDE EFFECTS: Side effects include:

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS: Nicotine gum is available in 2 and 4 mg strengths.

STORAGE: Nicotine gums should be stored at room temperature between 20 C to 25 C (68 F to 77 F).

DOSING:

  • Light smokers (less than 25 cigarettes per day): Use 1 piece of 2 mg gum every 1 to 2 hours for weeks 1 to 6; then use 1 piece of 2 mg every 2 to 4 hours for weeks 7 to 9; then use 1 piece of 2 mg gum every 4 to 8 hours for weeks 10 to 12.
  • Heavy smokers (more than 25 cigarettes per day): Use 1 piece of 4 mg gum every 1 to 2 hours for weeks 1 to 6; then use 1 piece of 4 mg every 2 to 4 hours for weeks 7 to 9; then use 1 piece of 4 mg gum every 4 to 8 hours for weeks 10 to 12.

Individuals should not use more than 24 pieces of nicotine gum per day. It is not recommended to eat or drink 15 minutes before or while chewing the gum. It is not recommended to use nicotine gum for more than 12 weeks.

Medically Reviewed by a Doctor on 2/25/2015

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