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January 8, 2009
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GENERIC NAME: NEVIRAPINE ORAL (neh-VYE-ruh-peen)

BRAND NAME(S): Viramune

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: See also How to Use, Precautions, and Notes sections. Nevirapine has infrequently caused severe (sometimes fatal) liver and skin reactions (e.g., Stevens-Johnson syndrome, allergic reaction), especially during the first 18 weeks of therapy. These reactions are most likely to occur during the first 6 weeks of therapy but can occur at any time while taking nevirapine. If you develop a rash at any time while using this medication, or if you develop unusual fatigue, abdominal or stomach pain, dark urine, loss of appetite, or yellowing of the skin or eyes, seek immediate medical attention (liver function tests should also be done at this time). If you had a severe liver or skin reaction while on this drug in the past, you should not restart therapy with nevirapine again. Consult your doctor or pharmacist for more details.

USES: This medication is used in the treatment of infection with the HIV virus (the virus that causes AIDS). It is used in combination with other HIV medications in selected patients. No cure exists for HIV infection, and the illnesses associated with your disease (infections, etc.) may continue. Because HIV can quickly become resistant to this medication if used alone, nevirapine must be used with at least 1 other anti-HIV medication. Your doctor may change your treatment plan if this medication stops working well.

HOW TO USE: Take by mouth as directed. The usual dose is one 200 mg tablet daily for the first 14 days, then followed by one 200 mg tablet twice a day. Nevirapine is taken with at least one other medication (antiretroviral) for HIV. It is important to follow the dosing instructions carefully in order to minimize serious side effects, such as rash. If a rash develops in the first two weeks, the nevirapine dose is not increased until the rash is gone. If treatment is stopped for more than 7 days, then re-treatment should begin as directed by your doctor, usually with one 200 mg tablet daily for 14 days, then one 200 mg tablet twice a day. Read the Patient Information Leaflet available from your pharmacist. If you have any questions, consult your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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