neomycin sulfate, polymyxin B sulfate, hydrocortisone acetate (Cortisporin, Otimar, Pediotic)

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GENERIC NAME: neomycin sulfate, polymyxin B sulfate, hydrocortisone acetate

BRAND NAME: Cortisporin, Otimar, Pediotic

DRUG CLASS AND MECHANISM: Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate is an antibacterial and anti-inflammatory ear drop. Neomycin and polymyxin are antibiotics that are active against gram positive and gram negative bacteria like Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species, Neisseria species, and Pseudomonas aeruginosa. Neomycin inhibits protein synthesis in bacteria, leading to bacterial cell death. Polymyxin alters bacterial cell wall structure so that cellular contents leak out and causes the bacteria to die. Hydrocortisone suppresses inflammation in the affected area. The FDA approved neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate in March, 1957.

SIDE EFFECTS: Side effects of neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate are:

PRESCRIBED FOR: Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate ear drops are used for treating bacterial infections of the external ear canal.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate ear drops are available in sterile suspension and solution forms in 10 ml bottles.

Medically Reviewed by a Doctor on 1/29/2015



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