neomycin sulfate, polymyxin B sulfate, hydrocortisone acetate (Cortisporin, Otimar, Pediotic)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: neomycin sulfate, polymyxin B sulfate, hydrocortisone acetate
BRAND NAME: Cortisporin, Otimar, Pediotic
DRUG CLASS AND MECHANISM: Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate is an antibacterial and anti-inflammatory ear drop. Neomycin and polymyxin are antibiotics that are active against gram positive and gram negative bacteria like Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species, Neisseria species, and Pseudomonas aeruginosa. Neomycin inhibits protein synthesis in bacteria, leading to bacterial cell death. Polymyxin alters bacterial cell wall structure so that cellular contents leak out and causes the bacteria to die. Hydrocortisone suppresses inflammation in the affected area. The FDA approved neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate in March, 1957.
SIDE EFFECTS: Side effects of neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate are:
PRESCRIBED FOR: Neomycin sulfate/polymyxin B sulfate/ hydrocortisone acetate ear drops are used for treating bacterial infections of the external ear canal.
Medically Reviewed by a Doctor on 1/29/2015
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