nelfinavir, Viracept (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DRUG INTERACTIONS: Nelfinavir interacts with many drugs because it reduces the ability of liver enzymes to break down certain drugs. Some of the important interactions are discussed below. Viewers should consult their health care professional before combining any drugs with nelfinavir.

Nelfinavir should not be used together with alfuzosin (Uroxatral), lovastatin (Mevacor), simvastatin (Zocor), pimozide (Orap), sildenafil (Revatio), amiodarone (Cordarone), quinidine (Quinaglute, Cardioquin), ergot derivatives (for example, Ergostat), triazolam (Halcion), and midazolam (Versed), because serious adverse effects could occur due to increased levels of these drug in the body.

Nelfinavir also may increase blood levels of vardenafil (Levitra, Staxyn), tadalafil (Cialis, Adcirca), and sildenafil (Viagra), leading to increased side effects. Dosage adjustments are recommended.

Medically Reviewed by a Doctor on 7/10/2015

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