nelfinavir, Viracept (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
DRUG INTERACTIONS: Nelfinavir interacts with many drugs because it reduces the ability of liver enzymes to break down certain drugs. Some of the important interactions are discussed below. Viewers should consult their health care professional before combining any drugs with nelfinavir.
Nelfinavir should not be used together with alfuzosin (Uroxatral), lovastatin (Mevacor), simvastatin (Zocor), pimozide (Orap), sildenafil (Revatio), amiodarone (Cordarone), quinidine (Quinaglute, Cardioquin), ergot derivatives (for example, Ergostat), triazolam (Halcion), and midazolam (Versed), because serious adverse effects could occur due to increased levels of these drug in the body.
Nelfinavir also increases the concentrations in blood of rifabutin (Mycobutin). Therefore, the doses of rifabutin should be reduced.
Rifampin and St. John's wort decrease the concentration of nelfinavir in the body and may reduce the effectiveness of nelfinavir.
Nelfinavir may decrease the effectiveness of oral contraceptives.
PREGNANCY: Nelfinavir has not been adequately evaluated in pregnant women.
NURSING MOTHERS: It is not known whether nelfinavir is secreted in breast milk. Nevertheless, HIV-infected mothers should not breastfeed because of the potential risk of transmitting HIV to an infant that is not infected.
Medically reviewed by Eni Williams, PharmD
Reference: FDA Prescribing Information
Medically Reviewed by a Doctor on 7/10/2015
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Back to Medications Index
- Allergic Skin Disorders
- Bacterial Skin Diseases
- Bites and Infestations
- Diseases of Pigment
- Fungal Skin Diseases
- Medical Anatomy and Illustrations
- Noncancerous, Precancerous & Cancerous Tumors
- Oral Health Conditions
- Papules, Scales, Plaques and Eruptions
- Scalp, Hair and Nails
- Sexually Transmitted Diseases (STDs)
- Vascular, Lymphatic and Systemic Conditions
- Viral Skin Diseases
- Additional Skin Conditions