nelfinavir, Viracept (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:



PREPARATIONS: Tablets: 250 and 625 mg; Oral powder: 50 mg/g

STORAGE: Capsules and powder should be stored at room temperature, 15 C to 30 C (59 F to 86 F). The oral powder should be consumed within 6 hours after mixing it with water or other liquids.

PRESCRIBED FOR: Nelfinavir is used in combination with other anti-HIV drugs for the treatment of HIV infection.

DOSING: The recommended dose for adults and adolescents 13 years and older is 1250 mg twice daily or 750 mg three times daily. The recommended dose for children 2-13 years of age is 25-35 mg/kg three times daily or 45 to 55 mg/kg twice daily. Nelfinavir should be administered with food or a light snack. The tablets may be crushed and dissolved in water or mixed with food. Once mixed in water or food, the mixture should be consumed within 6 hours.

DRUG INTERACTIONS: Nelfinavir interacts with many drugs because it reduces the ability of liver enzymes to break down certain drugs. Some of the important interactions are discussed below. Viewers should consult their health care professional before combining any drugs with nelfinavir.

Nelfinavir should not be used together with alfuzosin (Uroxatral), lovastatin (Mevacor), simvastatin (Zocor), pimozide (Orap), sildenafil (Revatio), amiodarone (Cordarone), quinidine (Quinaglute, Cardioquin), ergot derivatives (for example, Ergostat), triazolam (Halcion), and midazolam (Versed), because serious adverse effects could occur due to increased levels of these drug in the body.

Nelfinavir also may increase blood levels of vardenafil (Levitra, Staxyn), tadalafil (Cialis, Adcirca), and sildenafil (Viagra), leading to increased side effects. Dosage adjustments are recommended.

Nelfinavir also increases the concentrations in blood of rifabutin (Mycobutin). Therefore, the doses of rifabutin should be reduced.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index