nelfinavir, Viracept (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
PRESCRIBED FOR: Nelfinavir is used in combination with other anti-HIV drugs for the treatment of HIV infection.
SIDE EFFECTS: The most common side effects are
Other important side effects Nelfinavir include:
Nelfinavir oral powder contains phenylalanine and should be avoided by individuals with phenylketonuria. Like other protease inhibitors, use of nelfinavir may be associated with redistribution or accumulation of body fat, increased cholesterol and worsening of diabetes. Immune reconstitution syndrome, an inflammatory response to infection, may occur in patients treated with combinations of drugs for the treatment of HIV infection. There have been reports of spontaneous bleeding in patients with hemophilia treated with protease inhibitors.
GENERIC AVAILABLE: No
PREPARATIONS: Tablets: 250 and 625 mg; Oral powder: 50 mg/g
STORAGE: Capsules and powder should be stored at room temperature, 15 C to 30 C (59 F to 86 F). The oral powder should be consumed within 6 hours after mixing it with water or other liquids.
DOSING: The recommended dose for adults and adolescents 13 years and older is 1250 mg twice daily or 750 mg three times daily. The recommended dose for children 2-13 years of age is 25-35 mg/kg three times daily or 45 to 55 mg/kg twice daily. Nelfinavir should be administered with food or a light snack. The tablets may be crushed and dissolved in water or mixed with food. Once mixed in water or food, the mixture should be consumed within 6 hours.
Medically Reviewed by a Doctor on 7/10/2015
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