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- Patient Comments: Necrotizing Fasciitis - Cause
- Patient Comments: Necrotizing Fasciitis - Treatments
- Patient Comments: Necrotizing Fasciitis - Signs and Symptoms
- Patient Comments: Necrotizing Fasciitis - Diagnosis
- Patient Comments: Necrotizing Fasciitis - Experience
- Necrotizing fasciitis (flesh-eating disease) facts
- What is necrotizing fasciitis?
- Do different types of necrotizing fasciitis exist?
- What causes necrotizing fasciitis?
- What are necrotizing fasciitis symptoms and signs?
- How is necrotizing fasciitis diagnosed?
- What is the treatment for necrotizing fasciitis?
- How is necrotizing fasciitis prevented? Is necrotizing fasciitis contagious?
- Who is at risk to get necrotizing fasciitis?
- What is the prognosis (outcome) for patients with necrotizing fasciitis? What are complications of necrotizing fasciitis?
- What are some additional sources of information on necrotizing fasciitis?
Quick GuideBacterial Infections 101: Types, Symptoms, and Treatments
What is the prognosis (outcome) for patients with necrotizing fasciitis? What are complications of necrotizing fasciitis?
Untreated necrotizing fasciitis has a poor prognosis; death or severe morbidity (for example, limb loss) is the frequent outcome. Even with appropriate treatment, the mortality (death) rate can be as high as 25%. Infection with MRSA and other multidrug-resistant organisms tends to have higher morbidity and mortality rates. Combined mortality and morbidity (for example, limb loss, scar formation, renal failure, and sepsis) for all cases of necrotizing fasciitis has been reported as 70%-80%. Cases of Fournier's gangrene have reported as high as 75% mortality rates, while cases of Vibrio vulnificus-associated necrotizing fasciitis have about a 50% mortality rate. Fortunately, Vibrio vulnificus infection is relatively uncommon, but the incidence seems to be increasing. The U.S. Centers for Disease Control and Prevention (CDC), in 2007, made Vibrio vulnificus infection a reportable disease so the statistics on the incidence (frequency of occurrence) should be more easily obtained in the future.
The worst complication of this disease is rapid advancement that results in death. Other serious complications include tissue loss requiring surgical removal and amputation to limit disease, as well as sepsis, kidney failure, and extensive scarring.
What are some additional sources of information on necrotizing fasciitis?
"BBB - Aeromonas hydrophila," U.S. Food and Drug Administration
"Dermatologic Manifestations of Necrotizing Fasciitis," Medscape.com
Medically reviewed by Robert Cox, MD; American Board of Internal Medicine with subspecialty in Infectious Disease
Maynor, Michael E. "Emergent Management of Necrotizing Fasciitis." Medscape.com. Nov. 13, 2013. <http://emedicine.medscape.com/article/784690-overview>.
"Necrotizing Fasciitis (Flesh-Eating Bacteria)." WebMD.com. Feb. 10, 2011. <http://www.webmd.com/a-to-z-guides/necrotizing-fasciitis-flesh-eating-bacteria-topic-overview>.
United States. Centers for Disease Control and Prevention. "Necrotizing Fasciitis: A Rare Disease, Especially for the Healthy." June 28, 2013. <http://www.cdc.gov/features/necrotizingfasciitis/>.