PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: type 1 diabetes (insulin- dependent), diabetic ketoacidosis. Tell your doctor your medical history, especially of: liver disease, adrenal or pituitary gland problems, nerve disorders (e.g., autonomic neuropathy), gout, alcohol abuse, any allergies. Fever, serious infection or injury, or major surgery may increase your blood sugar level, temporarily decreasing the effectiveness of nateglinide. Consult your doctor for details. Caution is advised when this medication is used in the elderly, as they may be more sensitive to drug side effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially of: other diabetes medications (e.g., glyburide, rosiglitazone, tolbutamide), NSAIDs (e.g., ibuprofen, naproxen), "blood thinners" (e.g., warfarin), aspirin-like drugs (salicylates), MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), beta-blockers (e.g., propranolol), certain "water pills" (thiazide diuretics such as hydrochlorothiazide), corticosteroids (e.g., prednisone), sympathomimetic drugs (adrenaline-like medications such as pseudoephedrine), thyroid medication (e.g., levothyroxine). Alcohol may interact with the effects of this medication; if you drink alcohol, inform your doctor. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: severe sweating, unusually fast heartbeat, loss of consciousness.