Abdomen: The belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs . See the entire definition of Abdomen
Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ). See the entire definition of Abnormal
Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.) See the entire definition of Biopsy
Biotherapy: Treatment to stimulate or restore the ability of the immune (defense) system to fight infection and disease. Biological therapy is thus any form of treatment that uses the body's natural abilities that constitute the immune system to fight infection and disease or to protect the body from some of the side effects of treatment. See the entire definition of Biotherapy
Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres." See the entire definition of Brain
Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.
Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread). See the entire definition of Cancer
Cancer causes: In most individual cases of cancer, the exact cause of cancer is unknown. The causes may include increased genetic susceptibility; environmental insults, such as chemical exposure or smoking cigarettes; lifestyle factors, including diet; damage caused by infectious disease; and many more. See the entire definition of Cancer causes
Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast , colon, liver, lung, prostate, and stomach. See the entire definition of Carcinoma
Carcinoma in situ: Cancer that involves only the place in which it began and that has not spread. Carcinoma in situ is an early-stage tumor. See the entire definition of Carcinoma in situ
CAT scan : Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them in pictures on a screen. The CAT (computerized axial tomography) scan can reveal some soft-tissue and other structures that cannot even be seen in conventional X-rays. Using the same dosage of radiation as that of an ordinary X-ray machine, an entire slice of the body can be made visible with about 100 times more clarity with the CAT scan. See the entire definition of CAT scan
Chemotherapy : 1. In the original sense, a chemical that binds to and specifically kills microbes or tumor cells. The term chemotherapy was coined in this regard by Paul Ehrlich (1854-1915). 2. In oncology, drug therapy for cancer. Also called "chemo" for short. See the entire definition of Chemotherapy
Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum . See the entire definition of Chest
Clinical trial: See: Clinical trials. See also: Inconclusive clinical trial; Negative clinical trial; Non-inferior clinical trial; Positive clinical trial.
Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people. See the entire definition of Clinical trials
Collarbone: A horizontal bone above the first rib that makes up the front part of the shoulder. See the entire definition of Collarbone
Computerized tomography: Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them in pictures. See the entire definition of Computerized tomography
Cranial: 1. Pertaining to the cranium or skull. 2. Toward the head. As opposed to caudad. The eye is cranial to the jaw. For a more complete listing of terms used in medicine for spatial orientation, please see the entry to "Anatomic Orientation Terms".
Cranial nerves: Nerves that emerge from or enter the skull (the cranium), as opposed to the spinal nerves which emerge from the vertebral column. Cranial nerves come directly from the brain through the skull. See the entire definition of Cranial nerves
CT scan: Computerized tomography scan. Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them into pictures on a screen. CT stands for computerized tomography. See the entire definition of CT scan
Ear: The hearing organ. There are three sections of the ear, according to the anatomy textbooks. They are the outer ear (the part we see along the sides of our head behind the temples), the middle ear, and the inner ear. But in terms of function, the ear has four parts: those three and the brain. Hearing thus involves all parts of the ear as well as the auditory cortex of the brain. The external ear helps concentrate the vibrations of air on the ear drum and make it vibrate. These vibrations are transmitted by a chain of little bones in the middle ear to the inner ear. There they stimulate the fibers of the auditory nerve to transmit impulses to the brain. See the entire definition of Ear
Epstein-Barr virus: A virus , abbreviated EBV, best known as the cause of infectious mononucleosis (" mono "). See the entire definition of Epstein-Barr virus
Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.
External radiation therapy: Radiation therapy using a machine located outside the body to aim high-energy rays at a tumor.
Gland: 1. A group of cells that secrete a substance for use in the body. For example, the thyroid gland. 2. A group of cells that removes materials from the circulation. For example, a lymph gland.
Glucose: The simple sugar (monosaccharide) that serves as the chief source of energy in the body. Glucose is the principal sugar the body makes. The body makes glucose from proteins, fats and, in largest part, carbohydrates. Glucose is carried to each cell through the bloodstream. Cells, however, cannot use glucose without the help of insulin . Glucose is also known as dextrose. See the entire definition of Glucose
Immune: Protected against infection. The Latin immunis means free, exempt.
Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders. See the entire definition of Immune system
Immunotherapy: Treatment to stimulate or restore the ability of the immune (defense) system to fight infection and disease. Biological therapy is thus any form of treatment that uses the body's natural abilities that constitute the immune system to fight infection and disease or to protect the body from some of the side effects of treatment. See the entire definition of Immunotherapy
IMRT: Intensity modulated radiation therapy.
In situ: In the normal location. An "in situ" tumor is one that is confined to its site of origin and has not invaded neighboring tissue or gone elsewhere in the body. See the entire definition of In situ
Internal radiation therapy: Radiation therapy in which radioactive material is placed in or near a tumor.
Jawbone: 1. As a noun, a bone of the jaw, particularly the mandible. 2. As a verb, to try and influence with words (jawbones) rather than force.
Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems." See the entire definition of Laboratory
Lens: The transparent structure inside the eye that focuses light rays onto the retina (the nerve layer that lines the back of the eye, senses light and creates impulses that go through the optic nerve to the brain). The lens was named after the lentil bean because it resembled it in shape and size. See the entire definition of Lens
Lymph: An almost colorless fluid that travels through vessels called lymphatics in the lymphatic system and carries cells that help fight infection and disease.
Magnetic resonance imaging : A special radiology technique designed to image internal structures of the body using magnetism, radio waves, and a computer to produce the images of body structures. In magnetic resonance imaging (MRI), the scanner is a tube surrounded by a giant circular magnet. The patient is placed on a moveable bed that is inserted into the magnet. The magnet creates a strong magnetic field that aligns the protons of hydrogen atoms, which are then exposed to a beam of radio waves. This spins the various protons of the body, and they produce a faint signal that is detected by the receiver portion of the MRI scanner. A computer processes the receiver information, and an image is produced. The image and resolution is quite detailed and can detect tiny changes of structures within the body, particularly in the soft tissue, brain and spinal cord, abdomen and joints. See the entire definition of Magnetic resonance imaging
Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body. See the entire definition of Malignant
Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
MRI: Abbreviation and nickname for magnetic resonance imaging. For more information, see: Magnetic Resonance Imaging; Paul C. Lauterbur; Peter Mansfield.
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.
Nasopharynx: The area of the upper throat that lies behind the nose. In contrast to the oropharynx, the area of the throat that lies behind the mouth. See the entire definition of Nasopharynx
Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone. See the entire definition of Neck
Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.
Neurological: Having to do with the nerves or the nervous system.
Nose: The external midline projection from the face. See the entire definition of Nose
Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure. See the entire definition of Operation
Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye, ear, heart, lungs, and liver.
Oropharynx: The area of the throat that is at the back of the mouth. The oropharynx is in contrast to the nasopharynx, the part of the throat that lies behind the nose.
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors. See the entire definition of Pain
Palate: The roof of the mouth. The front portion is bony (hard palate), and the back portion is muscular (soft palate). See the entire definition of Palate
Pathologist: A doctor who identifies diseases by studying cells and tissues under a microscope.
PET scan: The popular name (and abbreviation) of Positron Emission Tomography.
Pharynx: The hollow tube about 5 inches long that starts behind the nose and ends at the top of the trachea (windpipe) and esophagus (the tube that goes to the stomach).
Pituitary: 1. As an adjective, pertaining to the pituitary gland or its hormonal secretions. 2. As a noun, the pituitary gland itself. See the entire definition of Pituitary
Pituitary gland: The main endocrine gland. It is a small structure in the head. It is called the master gland because it produces hormones that control other glands and many body functions including growth. The pituitary consists of the anterior and posterior pituitary. See the entire definition of Pituitary gland
Positron emission tomography: PET. A highly specialized imaging technique that uses short-lived radioactive substances to produce three-dimensional colored images of those substances functioning within the body. These images are called PET scans and the technique is termed PET scanning. See the entire definition of Positron emission tomography
Prognosis: 1. The expected course of a disease . 2. The patient's chance of recovery. The prognosis predicts the outcome of a disease and therefore the future for the patient . His prognosis is grim, for example, while hers is good. See the entire definition of Prognosis
Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.
Radiation therapy : The use of high-energy rays to damage cancer cells, stopping them from growing and dividing. Like surgery, radiation therapy is a local treatment that affects cancer cells only in the treated area. See the entire definition of Radiation therapy
Radioactive: Emitting energy waves due to decaying atomic nuclei. Radioactive substances are used in medicine as tracers for diagnosis, and in treatment to kill cancerous cells. See the entire definition of Radioactive
Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.
Registry: Although a registry was originally the place (like Registry House in Edinburgh) where information was collected (in registers), the word registry has also come to mean the collection itself. A registry is usually organized so the data can be analyzed. For example, analysis of data in a tumor registry maintained at a hospital may show a rise in lung cancer among women.
Scan: As a noun, the data or image obtained from the examination of organs or regions of the body by gathering information with a sensing device. See the entire definition of Scan
Skull: The skull is a collection of bones which encase the brain and give form to the head and face. The bones of the skull include the following: the frontal, parietal, occipital, temporal, sphenoid, ethmoid, zygomatic, maxilla, nasal, vomer, palatine, inferior concha, and mandible. See the entire definition of Skull
Soft palate: The muscular part of the roof of the mouth. The soft palate is directly behind the hard palate. It lacks bone and so is soft.
Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat . 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth. See the entire definition of Sore
Sore throat : Pain in the throat. Sore throat may be caused by many different causes, including inflammation of the larynx, pharynx, or tonsils. See the entire definition of Sore throat
Spinal cord: The major column of nerve tissue that is connected to the brain and lies within the vertebral canal and from which the spinal nerves emerge. Thirty-one pairs of spinal nerves originate in the spinal cord: 8 cervical , 12 thoracic , 5 lumbar, 5 sacral, and 1 coccygeal. The spinal cord and the brain constitute the central nervous system ( CNS ). The spinal cord consists of nerve fibers that transmit impulses to and from the brain. Like the brain, the spinal cord is covered by three connective-tissue envelopes called the meninges . The space between the outer and middle envelopes is filled with cerebrospinal fluid ( CSF ), a clear colorless fluid that cushions the spinal cord against jarring shock. Also known simply as the cord. See the entire definition of Spinal cord
Squamous cells: Flat cells that look like fish scales. The word "squamous" came from the Latin squama meaning "the scale of a fish or serpent." See the entire definition of Squamous cells
Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging . See the entire definition of Stage
Staging: In regard to cancer, the process of doing examinations and tests to learn the extent of the cancer, especially whether it has metastasized (spread) from its original site to other parts of the body.
Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine. See the entire definition of Stomach
Substance: 1. Material with particular features, as a pressor substance. 2. The material that makes up an organ or structure. Also known in medicine as the substantia. 3. A psychoactive drug as, for example, in substance abuse.
Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office. See the entire definition of Surgery
Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body. See the entire definition of Systemic
Therapy: The treatment of disease . See the entire definition of Therapy
Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth , consisting anatomically of the pharynx and larynx . The throat contains the trachea and a portion of the esophagus . See the entire definition of Throat
Thyroid: 1. The thyroid gland . Also, pertaining to the thyroid gland. 2. A preparation of the thyroid gland used to treat hypothyroidism . 3. Shaped like a shield. (The thyroid gland was so-named by Thomas Wharton in 1656 because it was shaped like an ancient Greek shield.) See the entire definition of Thyroid
Thyroid gland: A gland that makes and stores hormones that help regulate the heart rate, blood pressure, body temperature, and the rate at which food is converted into energy. Thyroid hormones are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions ( metabolism ) in the body. Thyroid hormones also help children grow and develop. See the entire definition of Thyroid gland
Tomography: The process for generating a tomogram , a two-dimensional image of a slice or section through a three-dimensional object. Tomography achieves this remarkable result by simply moving an x-ray source in one direction as the x-ray film is moved in the opposite direction during the exposure to sharpen structures in the focal plane, while structures in other planes appear blurred. The tomogram is the picture; the tomograph is the apparatus; and tomography is the process. See the entire definition of Tomography
Tongue: The tongue is a strong muscle anchored to the floor of the mouth. It is covered by the lingual membrane which has special areas to detect tastes. See the entire definition of Tongue
Tonsils: Small masses of lymphoid tissue at the back of the throat, on either side of the throat.
Trachea: A tube-like portion of the breathing or "respiratory" tract that connects the "voice box" (larynx) with the bronchial parts of the lungs. See the entire definition of Trachea
Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands). See the entire definition of Tumor
Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.
Vein: A blood vessel that carries blood low in oxygen content from the body back to the heart. The deoxygenated form of hemoglobin (deoxyhemoglobin) in venous blood makes it appear dark. Veins are part of the afferent wing of the circulatory system which returns blood to the heart. See the entire definition of Vein
Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult. See the entire definition of Virus
Windpipe: The trachea, a tube-like portion of the respiratory (breathing) tract that connects the larynx (the voicebox) with the bronchial parts of the lungs. See the entire definition of Windpipe
X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays. See the entire definition of X-ray
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