DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: blood thinners (e.g., warfarin, heparins), NSAID (e.g., ibuprofen, naproxen), cimetidine, acetazolamide, corticosteroids, methotrexate, medication for gout, drugs used for diabetes, sleeping pills, sedatives, anti-anxiety drugs (e.g., diazepam), anti-seizure drugs, muscle relaxants, drowsiness-causing antihistamines (e.g., diphenhydramine), all other pain relievers. Because this medication contains aspirin, check with your doctor or pharmacist before taking other medications containing aspirin or aspirin-related drugs. Aspirin is commonly found in pain relievers and cough-and-cold preparations, as are antihistamines. Read labels carefully to check ingredients. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include heartburn, stomach pain, muscle weakness, ringing in the ears, vomiting, slow or fast breathing, slow heart rate, or unconsciousness.

NOTES: To prevent constipation, increase your intake of fiber, drink plenty of water and exercise. Do not share this medication with others.

MISSED DOSE: If you miss a dose, take it as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature away from sunlight and moisture.

Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.