narcotic analgesic/aspirin/caffeine - oral (cont.)
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: ketorolac, mifepristone, naltrexone.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: acetazolamide, adenosine, antacids, anticholinergic medications (e.g., scopolamine), beta agonists (e.g., albuterol), "blood thinners" (e.g., warfarin, heparin, ticlopidine), certain antibiotics (e.g., penicillin, sulfonamides such as sulfamethoxazole, macrolide antibiotics such as erythromycin), certain anti-seizure medications (e.g., phenytoin, valproic acid), certain drugs used to treat gout (e.g., uricosuric drugs such as probenecid, sulfinpyrazone), cimetidine, corticosteroids (e.g., prednisone), diabetes drugs (e.g., sulfonylureas such as glyburide, insulin), disulfiram, drugs that lower blood pressure (e.g., "water pills"/diuretics such as hydrochlorothiazide, furosemide, ACE inhibitors such as lisinopril, enalapril), drugs that may affect hearing (e.g., vancomycin), ginkgo biloba, lepirudin, lithium, MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), 6-mercaptopurine, methotrexate, other medications for pain (e.g., pentazocine, nalbuphine, morphine), pemetrexed, salicylates (e.g., salsalate), certain antidepressants (SSRIs such as fluoxetine, fluvoxamine), zidovudine.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products, other headache medications) because they may contain aspirin, caffeine, or drowsiness-causing ingredients. Also keep in mind that certain beverages (e.g., coffee, colas, tea) contain caffeine. Ask your pharmacist about using those products safely.Also, check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as ibuprofen or naproxen) that are similar to this drug and may increase your risk for side effects if taken together with this medication.This medication may interfere with certain medical/laboratory tests (including fasting blood glucose, cholesterol levels, prothrombin time, urine 5-HIAA levels, amylase and lipase levels, certain urine glucose tests, dipyridamole-thallium imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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