naproxen, Anaprox, Naprelan, Naprosyn, Aleve (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. NSAIDs increase the risk of potentially fatal, stomach and intestinal adverse reactions (for example, bleeding, ulcers, and perforation of the stomach or intestines). Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Black tarry stools, weakness, and dizziness upon standing may be the only signs of the bleeding.

NSAIDs (except low dose aspirin) may increase the risk of potentially fatal heart attacks, stroke, and related conditions in people with or without heart disease or risk factors for heart disease. The increased risk of heart attack or stroke may occur as early as the first week of use and the risk may increase with longer use and is higher in patients who have underlying risk factors for heart and blood vessel disease. Therefore, NSAIDs should not be used for the treatment of pain resulting from coronary artery bypass graft (CABG) surgery.

PRESCRIPTION: Yes; (Aleve, no)



  • Anaprox (tablets): 275 and 550 mg
  • Naprosyn (tablets): 250, 375 and 500 mg
  • Naprosyn suspension: 125 mg/5ml
  • EC-Naprosyn: 375 mg
  • Aleve: 220 mg
  • Naprelan (controlled-release tablets): 375 and 500 mg.

STORAGE: Naproxen should be stored at room temperature: 15 C to 30 C (59 F to 86 F).

DOSING: The usual adult dose for pain is 250 every 6 to 8 hours or 500 mg twice daily using regular naproxen tablets. The usual dose for Naprelan controlled release tablets is 750 to 1000 mg given once daily. For EC-Naprosyn, the usual dose is 375-500 mg twice daily.

Medically Reviewed by a Doctor on 8/6/2015

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