GENERIC NAME: naloxone hydrochloride
BRAND NAME: Narcan, Evzio
GENERIC AVAILABLE: Yes
USES: Naloxone is used for partial or complete opioid competitive binding of mu-receptors to reverse respiratory depression and to treat opioid overdose symptoms. It is also used to increase blood pressure in people with septic shock.
SIDE EFFECTS: Side effects of Naloxone are:
- increase or decrease in blood pressure,
- abnormal heart rate and rhythm,
- troubled breathing,
- cardiac arrest,
- fluid retention in lungs, and
PREPARATIONS: Injection: 0.4 and 1 mg/ml; Auto Injector: 0.4 mg/0.4 ml
DRUG INTERACTIONS: Large doses of Naloxone are required when used together with buprenorphine since buprenorphine binds and dissociates slowly from mu receptors. Large doses of Naloxone may cause respiratory distress.
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