naloxone - hydrochloride injection (Narcan, Evzio)

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC NAME: naloxone hydrochloride

BRAND NAME: Narcan, Evzio

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES: Naloxone is used for partial or complete opioid competitive binding of mu-receptors to reverse respiratory depression and to treat opioid overdose symptoms. It is also used to increase blood pressure in people with septic shock.

SIDE EFFECTS: Side effects of Naloxone are:

PREPARATIONS: Injection: 0.4 and 1 mg/ml; Auto Injector: 0.4 mg/0.4 ml

DRUG INTERACTIONS: Large doses of Naloxone are required when used together with buprenorphine since buprenorphine binds and dissociates slowly from mu receptors. Large doses of Naloxone may cause respiratory distress.

Medically Reviewed by a Doctor on 1/22/2016



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