naloxone - hydrochloride injection (Narcan, Evzio)

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GENERIC NAME: naloxone hydrochloride

BRAND NAME: Narcan (Discontinued Brand in the US), Evzio

DRUG CLASS AND MECHANISM: Naloxone is a man-made opioid antagonist, which means that it blocks the action of opioid medications such as morphine and related drugs. Naloxone works by binding to mu-receptors in the brain that opioids use to produce their effect on pain and other symptoms. By binding to mu receptors naloxone reverses opioid activity in the body.



PREPARATIONS: Injection: 0.4 and 1 mg/ml; Auto Injector: 0.4 mg/0.4 ml

STORAGE: Store Naloxone injections at room temperature 20 C to 25 C (68 F to 77 F).

PRESCRIBED FOR: Naloxone is used for partial or complete opioid competitive binding of mu-receptors to reverse respiratory depression and to treat opioid overdose symptoms. It is also used to increase blood pressure in people with septic shock.

Medically Reviewed by a Doctor on 6/13/2014

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