nalbuphine (Nubain) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREGNANCY: There are no adequate studies of nalbuphine to determine safe and effective use in pregnant women. Nalbuphine should be used only if clearly needed and the benefit outweighs the risk to fetus. It is used during labor and delivery.

NURSING MOTHERS: Nalbuphine may enter breast milk in trace amount; therefore, it should be used with caution in mothers who are nursing.

SIDE EFFECTS: Side effects of Nalbuphine are sedation, dizziness, nausea, vomiting, dry mouth, headache, and low heart rate. Like other narcotics nalbuphine can cause respiratory depression (decreased rate or depth of breathing).

It may produce withdrawal in opioid dependent patients. Nalbuphine is a controlled substance and is habit forming. Mental and physical dependence can occur. Abruptly stopping the drug in patients who have been taking the drug for a long time can precipitate a withdrawal reaction. Symptoms of withdrawal include nausea, diarrhea, coughing, tearing, nasal discharge, profuse sweating, twitching muscles, and yawning.


FDA Prescribing Information.

Medscape. nalbuphine (Rx) - Nubain.

Medically Reviewed by a Doctor on 8/15/2014

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