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nalbuphine - injection, Nubain (cont.)

PRECAUTIONS: Before using nalbuphine, tell your doctor or pharmacist if you are allergic to it; or to preservatives such as parabens; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: abdominal problems (e.g., gallbladder disease, pancreatitis, recent surgery), adrenal gland problems (e.g., Addison's disease), brain disorders (e.g., seizures, head injury, tumor, increased intracranial pressure), severe breathing problems (e.g., respiratory depression, hypercapnia, hypoxia), intoxication with alcohol or medications that depress the nervous system or your breathing (CNS/respiratory depressants such as tranquilizers/sedatives), slow gut movement (e.g., chronic constipation, paralytic ileus), heart problems (e.g., irregular heartbeat, recent heart attack), severe infectious diarrhea (e.g., Clostridium difficile-associated diarrhea), lung diseases (e.g., asthma, chronic obstructive pulmonary disease-COPD), physical dependence on narcotics, kidney disease, liver disease, mental/mood disorders (e.g., toxic psychosis), a certain spinal problem (kyphoscoliosis), personal or family history of regular use/abuse of drugs/alcohol, difficulty urinating (e.g., due to enlarged prostate or urethral stricture), underactive thyroid (hypothyroidism).This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be more sensitive to the effects of this drug, especially confusion and drowsiness.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Using it for long periods or in high doses near the expected delivery date is not recommended because of possible harm to the unborn baby. Infants born to mothers who have used this medication for an extended time may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, or diarrhea. Tell your doctor immediately if you notice any of these symptoms in your newborn.Nalbuphine may be used during labor. It is not recommended for use within 4 hours of the expected time of delivery because there is a risk of temporary problems with breathing and heartbeat in the newborn. Discuss the risks and benefits with your doctor.This drug may pass into breast milk. Consult your doctor before breast-feeding.



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