nadolol, Corgard (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREGNANCY: Safe use of nadolol during pregnancy has not been established.

NURSING MOTHERS: Nadolol is excreted into breast milk. Nadolol should not be used while breastfeeding because of the potential risk of adverse effects in the nursing infant.

SIDE EFFECTS: Nadolol is generally well tolerated. Side effects include abdominal cramps, diarrhea, constipation, fatigue, insomnia, nausea, depression, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, and shortness of breath or wheezing. Nadolol can aggravate breathing difficulties in patients with asthma, chronic bronchitis, or emphysema.

In patients with existing slow heart rates (bradycardias) and heart blocks (defects in the electrical conduction of the heart), nadolol can cause dangerously slow heart rates, and even shock. Nadolol reduces the force of heart muscle contraction and can aggravate symptoms of heart failure. In patients with coronary artery disease, abruptly stopping nadolol can suddenly worsen angina and occasionally precipitate heart attacks. If it is necessary to discontinue nadolol, its dose should be reduced gradually over several weeks.

Reference: FDA Prescribing Information

Last Editorial Review: 3/26/2009

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