Nadh

• What other names is Nadh known by?
• What is Nadh?
• How does Nadh work?
• Are there safety concerns?
• Dosing considerations for Nadh.

What other names is Nadh known by?

B-DPNH, BNADH, Coenzyme 1, Enada, NAD, Nicotinamide Adénine Dinucléotide, Nicotinamide Adenine Dinucleotide Hydrate, Reduced DPN, Reduced Nicotinamide Adenine Dinucleotide.

What is Nadh?

NADH stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H)." This chemical occurs naturally in the body and plays a role in the chemical process that generates energy. People use NADH supplements as medicine.

NADH is used for improving mental clarity, alertness, concentration, and memory; as well as for treating Alzheimer's disease. Because of its role in energy production, NADH is also used for improving athletic endurance and treating chronic fatigue syndrome (CFS).

Some people use NADH for treating high blood pressure, high cholesterol, jet lag, depression, and Parkinson's disease; boosting the immune system; opposing alcohol's effects on the liver and the hormone testosterone; reducing signs of aging; and protecting against the side effects of an AIDS drug called zidovudine (AZT).

Healthcare providers sometimes give NADH by intramuscular (IM) or intravenous (IV) injection for Parkinson's disease and depression.

Possibly Ineffective for...

• Mental decline (dementia) related to Alzheimer's disease and other conditions.

Insufficient Evidence to Rate Effectiveness for...

• Chronic fatigue syndrome (CFS). There is some early evidence that NADH might reduce the symptoms of CFS when used along with traditional medications.
• Parkinson's disease. So far, study results don't agree about the effectiveness of NADH in treating Parkinson's disease.
• Depression.
• Jet lag.
• High blood pressure.
• Improving athletic performance.
• Increasing energy.
• Improving memory and concentration.
• Boosting immune function.
• Reducing signs of aging.
• Lowering cholesterol levels.
• Protecting against side effects of the drug zidovudine (AZT) used to treat AIDS.
• Other conditions.

More evidence is needed to rate the effectiveness of NADH for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).