mupirocin, mupirocin calcium (cont.)

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PREPARATIONS: Topical Ointment:  2% (20 mg/g). Topical Cream:  2% (20 mg/g). Nasal ointment:  2% (20 mg/g).

STORAGE: Tablets should be stored at room temperature, 15 C-30 C (59 F-86 F).

PRESCRIBED FOR: Mupirocin is used for the treatment of impetigo and infections of the skin caused by Staphylococcus aureus, beta-hemolytic streptococcus or Streptococcus pyogenes. Mupirocin is not recommended for use on the skin in serious burns, because more of the vehicle (the inactive ingredient) used for the ointment, polyethylene glycol (Miralax), may be absorbed and can damage the kidneys. The nasal ointment  is used for the elimination of nasal Staphylococcus aureus that have become resistant to other antibiotics. Mupirocin also may be used for other infections as determined by the physician.

DOSING: For the treatment of impetigo, a small amount of the ointment is applied to the affected area, usually three times daily (every 8 hours). The area may be covered with a sterile gauze dressing. If there is no improvement in 3-5 days, the physician should be contacted to re-examine the infected area. For other skin infections, the cream is applied to the affected area 3 times a day for 10 days, and the doctor should be contacted as well if there is no improvement after 3-5 days.

When mupirocin is used for treating intranasal Staphylococcus aureus that are resistant to other antibiotics, patients who are age 12 years and older require the application of about half of the ointment from a single-use tube of ointment into one nostril and the other half into the other nostril. This treatment is repeated twice daily for 5 days. Currently, there is not enough information to recommend use of mupirocin in children younger than 12 years of age.

DRUG INTERACTIONS: There are no known drug interactions with mupirocin; however, it should not be used at the same time with other drugs that are applied inside the nose.

Medically Reviewed by a Doctor on 10/8/2014

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