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diarrhea, bloating, fatigue, headache, insomnia, itching, or worsening of allergy symptoms.
There isn't enough information to know if MSM is safe when applied to the skin, as in creams, lotions, or nose drops.
Do not use MSM if:
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.