GENERIC NAME: moxifloxacin hydrochloride
BRAND NAME: Avelox
DRUG CLASS AND MECHANISM: Moxifloxacin is a fluoroquinolone antibiotic. Other fluoroquinolones include ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin). Moxifloxacin works by blocking DNA gyrase enzyme, which is responsible for production and repair of bacterial DNA. Blocking of DNA gyrase leads to bacteria death and prevents worsening of infection. Moxifloxacin treats infections caused by gram-positive and gram-negative bacteria like Streptococcus anginosus, Streptococcus constellatus, Streptococcus pneumonia, Enterobacter cloacae, Escherichia coli, Haemophilus influenza, Klebsiella pneumonia, and Moraxella catarrhalis. Moxifloxacin also treats infections caused by Clostridium perfringens, Chlamydophila pneumonia, and Mycoplasma pneumonia. FDA approved brand name moxifloxacin (Avelox) in December 1999.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 400 mg. Injection: 400 mg/250 ml
STORAGE: Store moxifloxacin tablets between temperatures of 20 C to 25 C (68 F to 77 F).
PRESCRIBED FOR: Moxifloxacin is used for treating bacterial sinus infection, bronchitis, community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections, and complicated intra-abdominal infections.
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