moxifloxacin, Avelox

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jerry R. Balentine, DO, FACEP
    Jerry R. Balentine, DO, FACEP

    Jerry R. Balentine, DO, FACEP

    Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.

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GENERIC NAME: moxifloxacin hydrochloride

BRAND NAME: Avelox

DRUG CLASS AND MECHANISM: Moxifloxacin is a fluoroquinolone antibiotic. Other fluoroquinolones include ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin). Moxifloxacin works by blocking DNA gyrase enzyme, which is responsible for production and repair of bacterial DNA. Blocking of DNA gyrase leads to bacteria death and prevents worsening of infection. Moxifloxacin treats infections caused by gram-positive and gram-negative bacteria like Streptococcus anginosus, Streptococcus constellatus, Streptococcus pneumonia, Enterobacter cloacae, Escherichia coli, Haemophilus influenza, Klebsiella pneumonia, and Moraxella catarrhalis. Moxifloxacin also treats infections caused by Clostridium perfringens, Chlamydophila pneumonia, and Mycoplasma pneumonia. FDA approved brand name moxifloxacin (Avelox) in December 1999.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 400 mg. Injection: 400 mg/250 ml

STORAGE: Store moxifloxacin tablets between temperatures of 20 C to 25 C (68 F to 77 F).

PRESCRIBED FOR: Moxifloxacin is used for treating bacterial sinus infection, bronchitis, community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections, and complicated intra-abdominal infections.

Medically Reviewed by a Doctor on 10/7/2014

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