morphine high potency injection (Astramorph, Duramorph, Infumorph, AVINza)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is morphine high potency injection, and how does it work (mechanism of action)?

Morphine is a chemical found in the opium plant. It is a narcotic (opiod) pain-reliever similar to hydrocodone, oxycodone, methadone, fentanyl, and other opioids. Morphine, like other opioids, stimulates receptors on nerves in the brain to increase the threshold to pain (increasing the amount of stimulation it takes to feel pain) and reduce the perception of pain (the perceived importance of the pain). The FDA approved injectable morphine in October 1986.

What brand names are available for morphine high potency injection?

Astramorph, Duramorph, Infumorph, AVINza

Is morphine high potency injection available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for morphine high potency injection?

Yes

What are the side effects of morphine high potency injection?

The most frequent adverse reactions of morphine include:

Other side effects include:

Patients may also develop anemia with intrathecal injection, and pain at the injection site. The elderly may be more sensitive to adverse effects. Morphine has the potential to be habit forming. Tolerance and physical and psychological dependence may occur with prolonged use. Seizures may result from high doses. Overdoses may cause respiratory depression, coma, and death.

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