morphine high potency injection (Astramorph, Duramorph, Infumorph, AVINza)

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Medical and Pharmacy Editor:

GENERIC NAME: Morphine for injection

BRAND NAMES: Astramorph, Duramorph, Infumorph, AVINza

DRUG CLASS AND MECHANISM: Morphine is a chemical found in the opium plant. It is a narcotic (opiod) pain-reliever similar to hydrocodone, oxycodone, methadone, fentanyl, and other opioids. Morphine, like other opioids, stimulates receptors on nerves in the brain to increase the threshold to pain (increasing the amount of stimulation it takes to feel pain) and reduce the perception of pain (the perceived importance of the pain). The FDA approved injectable morphine in October 1986.

PRESCRIBED FOR: Morphine through intravenous, epidural, or intrathecal injections is used for the management of moderate-to-severe acute and chronic pain that is not responsive to non-narcotic pain relievers.

SIDE EFFECTS: The most frequent adverse reactions of morphine include:

  • dry mouth,
  • constipation,
  • nausea,
  • vomiting,
  • drowsiness,
  • dizziness, and
  • difficulty urinating.

Other side effects include:

Medically Reviewed by a Doctor on 3/19/2015



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