mometasone furoate, Nasonex

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: mometasone furoate nasal inhaler/spray

BRAND NAME: Nasonex

DRUG CLASS AND MECHANISM: Mometasone furoate is a synthetic (man-made) steroid hormone in the glucocorticoid family of steroid hormones that is used for the treatment of nasal allergy. The naturally occurring glucocorticoid hormone is cortisol or hydrocortisone which is produced in the adrenal glands. Glucocorticoid hormones are potent reducers of inflammation (anti-inflammatory). When used as a nasal inhaler or spray, medications travel directly to the inner lining of the nose, and very little is absorbed into the body to cause side effects. The FDA approved mometasone in October 1997.

PRESCRIBED FOR: Mometasone furoate is used in individuals 2 years of age or older for control of the symptoms of allergic rhinitis, an inflammation of the nose in which the inner lining of the nose swells and releases fluid (mucus). It is used for controlling symptoms of seasonal allergic rhinitis as well as prevention of seasonal allergic rhinitis in patients 12 years old or older. It also is used for treatment of nasal polyps in patients 18 years of age or older.

SIDE EFFECTS: The most common side effects associated with nasal mometasone furoate are:

  • headache,
  • nasal irritation,
  • sneezing, and, occasionally,
  • bleeding from the nose.

Nasal septal perforation, fungal infection of the nose, and disturbances of taste and smell have been reported. Higher doses of mometasone may cause suppression of the body's ability to make its own natural glucocorticoid in the adrenal gland. People with suppression of their adrenal glands (which can be diagnosed by a doctor) would need increased amounts of glucocorticoids, probably by the oral or intravenous route, during periods of high physical stress or acute illness when glucocorticoids are particularly important. Intranasal steroids may cause growth suppression, weaken the immune system, and may increase the risk of glaucoma, and cataracts.

Medically Reviewed by a Doctor on 3/19/2015

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