mitoxantrone (Novantrone)

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC NAME: mitoxantrone


DRUG CLASS AND MECHANISM: Mitoxantrone is a synthetic (man-made) anticancer drug. It kills cancer cells by disrupting the action of deoxyribonucleic acids (DNA) in human cells by causing abnormal cross-links and breaks in the DNA. It also interferes with ribonucleic acid (RNA) and inhibits the activity of topoisomerase II, an enzyme that is necessary for repairing damaged DNA. The FDA approved mitoxantrone in December 1987.

PRESCRIBED FOR: Mitoxantrone is used for treating secondary progressive multiple sclerosis, acute nonlymphocytic leukemia, and patients with pain related to advanced hormone-refractory prostate cancer.

SIDE EFFECTS: The most common side effects of mitoxantrone are:

Medically Reviewed by a Doctor on 7/9/2015

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index