GENERIC NAME: MITOTANE - ORAL (MYE-toe-tane)
BRAND NAME(S): Lysodren
WARNING: Mitotane causes your body to decrease its ability to quickly respond to stress (shock, severe injury, or infection). Mitotane may need to be stopped if you experience an injury, infection, or other stress. Your doctor may also prescribe another medication (corticosteroid).
USES: Mitotane is used to treat cancer of the adrenal glands. The adrenal glands produce hormones, which are needed by the body to deal with stress, fight infection, and maintain normal functions such as blood pressure. Certain cancers cause the adrenal glands to produce too much cortisol and other hormones, causing a certain serious condition (Cushing's syndrome). Too much of these hormones can cause many problems such as blood pressure changes, weight changes, muscle/bone weakness, thinning skin, and diabetes. Mitotane works by killing or slowing the growth of adrenal gland cells and also reverses the side effects caused by too much hormone production.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used alone or with other medications to treat other forms of Cushing's syndrome not caused by adrenal cancer (e.g., non-pituitary tumor).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.