mirtazapine, Remeron, Soltab (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Mirtazapine should not be used with monoamine oxidase (MAO) inhibiting drugs such as phenelzine (Nardil), procarbazine (Matulane), selegiline (Eldepryl), or tranylcypromine (Parnate). High fever, convulsions, and even death can occur from such combinations. Therefore, an interval of 14 days is recommended between stopping MAO inhibitor therapy and starting mirtazapine, and vice versa. Similar reactions may occur if mirtazapine is combined with other drugs that increase serotonin activity in the brain. Such drugs to avoid include tryptophan, sumatriptan (Imitrex), linezolid (Zyvox), fluoxetine (Prozac), venlafaxine (Effexor), lithium (Eskalith, Lithobid), tramadol (Ultram), and St. John's wort.

PREGNANCY: There are no adequate studies of mirtazapine in pregnant women. Thus, physicians must balance potential benefits against potential risks when considering mirtazapine therapy in pregnant women.

NURSING MOTHERS: It is not known if mirtazapine is secreted in breast milk.

SIDE EFFECTS: Common side effects of mirtazapine include drowsiness, dry mouth, weight gain, increased appetite, increased cholesterol and triglycerides, dizziness, constipation, confusion, and abnormal dreams. Serious side effects include seizures, abnormal heart beats, low blood pressure upon standing (orthostatic hypotension), manic episodes, and decreased blood cells.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index