PREGNANCY AND BREASTFEEDING SAFETY: Minocycline should be avoided in pregnant women because it crosses the placenta and may cause fetal harm.
Minocycline is excreted in human milk, and there is potential for serious adverse effects involving the development of teeth and bones in nursing infants. A decision should be made to discontinue medication or stop nursing, taking into account the importance of the drug to the mother.
PREPARATIONS: Tablets and Capsules: 50, 75, and 100 mg. Tablets (Extended Release): 45, 55, 65, 80, 90, 105, 115, and 135 mg. Injection: 100 mg/ vial.
STORAGE: Minocycline immediate-release tablets and capsules should be stored between 20 C-25 C (68 F-77 F). Minocycline extended-release tablets should be stored between 15 C -30 C (59 F-86 F).
How does minocycline work? Minocycline is a member of the tetracycline family of antibiotics. It is similar to doxycycline (Vibramycin). It works by interrupting the production of proteins by bacteria. It is effective against a wide variety of bacteria, such as Mycoplasma pneumonia, Chlamydia trachomatis, Borrelia recurrentis, Yersinia pestis, Escherichia coli, and many others. The FDA approved minocycline in June, 1971.
Medically reviewed by Eni Williams, PharmD, PhD
REFERENCE: FDA Prescribing Information
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