milnacipran, Savella (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:
Medical and Pharmacy Editor:

PREGNANCY: There are no adequate studies in pregnant women. Milnacipran should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

NURSING MOTHERS: Milnacipran is excreted in human breast milk. The effect of milnacipran on nursing infants is not known. Breastfeeding should probably be avoided while taking milnacipran.

SIDE EFFECTS: The most frequent side effects include nausea, headache, constipation, dizziness, insomnia, flushing, excessive sweating, vomiting, palpitations, increased heart rate, dry mouth, and high blood pressure. Other side effects include seizures, hypertensive crisis, abnormal bleeding, low blood sodium (hyponatremia), and withdrawal syndrome.

Antidepressants may increase the risk of suicidal thinking and behavior in children and adolescents with depression. Patients who are started on milnacipran or another antidepressant should be observed closely for clinical worsening, suicidal thinking and behavior, or unusual behavior.

Reference: FDA Prescribing Information.


Medically Reviewed by a Doctor on 8/15/2014


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