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Migraine Headache

Medical Author: Dennis Lee, MD
Medical Editors: Harley I. Kornblum, MD, PhD, Jay W. Marks, MD

Migraine Pain, Go Away!

Understanding Migraine Headaches

A migraine headache usually is aggravated by daily activities like walking upstairs. Nausea, vomiting, diarrhea, facial pallor, cold hands, cold feet, and sensitivity to light and sound commonly accompany migraine headaches. As a result of this sensitivity to light and sound, migraine sufferers usually prefer to lie in a quiet, dark room during an attack. A typical attack lasts between 4 and 72 hours.


Effective Treatments for Migraine Pain

I used to suffer about 30 excruciating migraines a month. I was placed on Inderal and Topamax. I now suffer about 12 to18 per month. When the actual migraine hits, I usually take two Midrin and lie down in a dark room. If that doesn't work, I take one more Midrin and drink a Mountain Dew and continue to lie down. Usually that works. While in bed, I try to think of something soothing and relaxing that takes my mind away from the pain. About 50% of the time this works. I also take Zofran for nausea.


Read More Effective Treatments from Other Patients »

What is a migraine headache?

A migraine headache is a form of vascular headache. Migraine headache is caused by a combination of vasodilatation (enlargement of blood vessels) and the release of chemicals from nerve fibers that coil around the blood vessels. During a migraine attack, the temporal artery enlarges. (The temporal artery is an artery that lies on the outside of the skull just under the skin of the temple.) Enlargement of the temporal artery stretches the nerves that coil around the artery and causes the nerves to release chemicals. The chemicals cause inflammation, pain, and further enlargement of the artery. The increasing enlargement of the artery magnifies the pain.

Migraine attacks commonly activate the sympathetic nervous system in the body. The sympathetic nervous system is often thought of as the part of the nervous system that controls primitive responses to stress and pain, the so-called "fight or flight" response. The increased sympathetic nervous activity in the intestine causes nausea, vomiting, and diarrhea. Sympathetic activity also delays emptying of the stomach into the small intestine and thereby prevents oral medications from entering the intestine and being absorbed. The impaired absorption of oral medications is a common reason for the ineffectiveness of medications taken to treat migraine headaches. The increased sympathetic activity also decreases the circulation of blood, and this leads to pallor of the skin as well as cold hands and feet. The increased sympathetic activity also contributes to the sensitivity to light and sound sensitivity as well as blurred vision.

Migraine afflicts 28 million Americans, with females suffering more frequently (17%) than males (6%). Missed work and lost productivity from migraine create a significant public burden. Nevertheless, migraine still remains largely undertreated and underdiagnosed. Less than half the sufferers are diagnosed by their doctors.



Next: What are the symptoms of migraine headaches? »

Migraine Headache - Effective Treatments

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