miglitol, Glyset

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GENERIC NAME: miglitol

BRAND NAME: Glyset

DRUG CLASS AND MECHANISM: Miglitol is an oral medication used to control blood glucose (sugar) levels in type 2 diabetes. It belongs to a class of drugs called alpha-glucosidase inhibitors which also includes acarbose (Precose). Carbohydrates that are eaten are digested by enzymes in the intestine into smaller sugars which are absorbed into the body and raise blood sugar levels. The process of carbohydrate digestion requires the pancreas to release into the intestine alpha-amylase enzymes which digest the large carbohydrates into smaller carbohydrates called oligosaccharides. The cells lining the small intestine then release alpha-glucosidase enzymes that further digest the oligosaccharides into smaller sugars, like glucose, that can be absorbed. Miglitol is a man-made oligosaccharide designed to slow down the actions of alpha-amylase and alpha-glucosidase enzymes thereby slowing the appearance of sugar in the blood after a meal. The FDA approved miglitol in December 1996.

GENERIC: No

PRESCRIPTION: Yes

PREPARATIONS: Tablets: 25, 50 and 100 mg.

STORAGE: Miglitol should be stored at room temperature, 15 C to 30 C (59 F to 86 F), in a tight container.

PRESCRIBED FOR: It is believed that strict control of blood sugar in people with diabetes decreases the risk of eye, kidney, and nerve damage. Alpha-glucosidase inhibitors are used to help control blood sugar levels that are not controlled by diet and exercise alone. Miglitol is used for treating type 2 diabetes alone or in combination with a sulfonylurea such as glyburide (Diabeta).

Medically Reviewed by a Doctor on 3/6/2013



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