- What is midazolam-injection, and how does it work (mechanism of action)?
- Is midazolam-injection available as a generic drug?
- Do I need a prescription for midazolam-injection?
- What are the uses for midazolam-injection?
- What are the side effects of midazolam-injection?
- What is the dosage for midazolam-injection?
- Which drugs or supplements interact with midazolam-injection?
- Is midazolam-injection safe to take if I'm pregnant or breastfeeding?
- What else should I know about midazolam-injection?
What is the dosage for midazolam-injection?
Midazolam is given by intramuscular or intravenous injection. The dose for sedation during surgery is 0.5 to 1 mg given over 2 minutes and not to exit 2.5 mg per dose. Doses may be repeated after 2 to 3 minutes. Total doses greater than 5 mg usually are not needed. The dose for starting anesthesia is 200 to 350 mcg/kg injected intravenously over 20 to 30 seconds.
Which drugs or supplements interact with midazolam-injection?
Midazolam and all benzodiazepines interact with other medications and drugs that slow the brain's processes such as alcohol, barbiturates, narcotics, and tranquilizers. Boceprevir (Victrelis), itraconazole (Sporanox), nelfinavir (Viracept), and telaprevir (Incivek) increase blood level of midazolam by reducing its breakdown in the liver and, therefore can increase the side effects of midazolam.
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