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GENERIC NAME: MIBEFRADIL - ORAL (my-BEFF-ruh-dill)

BRAND NAME(S): Posicor

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This drug is a calcium channel blocker. Calcium is involved in blood vessel contraction. By blocking calcium, mibefradil relaxes and widens the blood vessels. It is used to treat high blood pressure or chest pain (angina). This drug has been withdrawn from the U.S. market due to safety or effectiveness problems.

HOW TO USE: This drug is usually taken once daily by mouth. Follow directions exactly and do not stop taking this medication without first checking with your doctor or pharmacist. Tablets should be swallowed whole and not chewed or crushed. The full effect of the drug should occur after taking this for 1 to 2 weeks. When switching from mibefradil to certain other blood pressure medicines, it is advised to stop the mibefradil for a period of time before starting the new medicine. Consult your doctor.

SIDE EFFECTS: Generally this drug is well tolerated. Dizziness, headache, leg swelling, abdominal pain, nausea, unusual fatigue or nasal congestion might occur. If these persist or worsen, notify your doctor promptly. Very unlikely but report promptly: fainting spells, very slow heartbeat, breathing difficulties, skin rash. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), heart conditions, very low blood pressure, liver problems. To lessen the possible problem of feeling dizzy upon standing, stand up slowly from a lying or sitting position. This medication should be used only when clearly needed during pregnancy. Avoid use around the time of labor and birth. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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Suggested Reading by Our Doctors
MedicineNet Doctors
  • High Blood Pressure - Learn about high blood pressure symptoms like headache, dizziness, shortness of breath, blurred vision and more. Causes, and normal blood pressure information is included.
  • Angina - Learn about the causes and symptoms of angina like pressure, heaviness, tightening, squeezing, and aching across the chest. There are two types of angina, stable (the most common) and unstable.

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mibefradil-oral, Posicor

What is high blood pressure?

High blood pressure (HBP) or hypertension means high pressure (tension) in the arteries. Arteries are vessels that carry blood from the pumping heart to all the tissues and organs of the body. High blood pressure does not mean excessive emotional tension, although emotional tension and stress can temporarily increase blood pressure. Normal blood pressure is below 120/80; blood pressure between 120/80 and 139/89 is called "pre-hypertension", and a blood pressure of 140/90 or above is considered high.

The top number, the systolic blood pressure, corresponds to the pressure in the arteries as the heart contracts and pumps blood forward into the arteries. The bottom number, the diastolic pressure, represents the pressure in the arteries as the heart relaxes after the contraction. The diastolic pressure reflects the lowest pressure to which the arteries are exposed.

An elevation of the systolic and/or diastolic blood pressure increas...

Read the High Blood Pressure article »



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