Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
DRUG CLASS AND MECHANISM: Metronidazole cream is a topical (applied to the skin) preparation of the antibiotic metronidazole. It is used for reducing the swelling and redness caused by
acne rosacea. The mechanism through which metronidazole cream reduces the symptoms of acne rosacea is not known.
PRESCRIPTION: yes
GENERIC AVAILABLE: No
PREPARATIONS: Cream, 30 grams
STORAGE: Store at room temperature 20-25 C (68-77 F)
PRESCRIBED FOR: Metronidazole cream is used for the topical treatment of swelling and redness caused by acne rosacea. Metronidazole cream also reduces the number of acne rosacea lesions.
DOSING: Metronidazole cream is applied and rubbed into the affected areas once daily. Makeup may be used after metronidazole cream has been applied. Metronidazole cream is for external use only. Contact with the eyes should be avoided.
DRUG INTERACTIONS: Drug interactions with metronidazole cream are unlikely because only small amounts of it are absorbed into the body when metronidazole cream is applied to the skin.
PREGNANCY: There are no adequate studies of metronidazole cream in
pregnant women.
NURSING MOTHERS: When metronidazole is administered orally it is secreted into
breast milk in concentrations similar to the concentration in the mothers body. Therefore, small amounts of metronidazole that are absorbed into the body when metronidazole cream is used may be secreted into breast milk.
SIDE EFFECTS: Side effects are rare and minor. Some patients may experience irritation at the site of application. Individuals that are allergic to metronidazole should not use metronidazole cream.
Bacterial vaginosis is an abnormal vaginal condition that is characterized by vaginal discharge resulting from an overgrowth of normal bacteria in the vagina. Although it may cause some disturbing symptoms (discharge and odor), it is not dangerous and cannot be passed by sex. Diagnosis becomes important to exclude serious infections like gonorrhea and Chlamydia. Many treatment options are available such as oral antibiotics and vaginal gels.
Rosacea is a skin disease that causes redness of the forehead, chin, and lower half of the nose. In addition to inflammation of the facial skin, symptoms include dilation of the blood vessels and pimples (acne rosacea) in the middle third of the face. Oral and topical antibiotics are treatments for rosacea. If left untreated, rhinophyma (a disfiguring nose condition) may result.
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