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November 24, 2009
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METOPROLOL-ORAL (cont.)

DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: mibefradil, psychiatric drugs (phenothiazines such as chlorpromazine, thioridazine). If you are currently using any of these medications, tell your doctor or pharmacist before starting this drug. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: alpha-blockers (e.g., prazosin), anti-diabetic drugs (e.g., glipizide, glyburide, insulin), barbiturates (e.g., phenobarbital), calcium channel blockers (e.g., diltiazem, verapamil), cimetidine, epinephrine, general anesthesia, non-steroidal anti-inflammatory drugs (e.g., indomethacin, ibuprofen), other heart drugs (e.g., amiodarone, digoxin, propafenone, quinidine, intravenous lidocaine), other drugs to treat high blood pressure (e.g., clonidine, hydralazine, reserpine), medications for overactive thyroid disease (e.g., methimazole, propylthiouracil), paroxetine, rifamycins (e.g., rifampin), St. John's wort. Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include unusually slow heartbeat, severe dizziness, slow or shallow breathing, weakness, or fainting.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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