DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: drugs affecting liver enzymes that remove methysergide from your body (e.g., azole antifungals such as ketoconazole, itraconazole, voriconazole, macrolide antibiotics such as erythromycin, clarithromycin, HIV drugs such as delavirdine, efavirenz, indinavir, nelfinavir, ritonavir), other ergot alkaloids (e.g., ergonovine), smoking/nicotine products (e.g., patches, gum), sibutramine.If you also take "triptan" migraine drugs (e.g., sumatriptan, rizatriptan), you will need to separate your "triptan" dose from your dose of this medication to reduce the risk of serious side effects. Ask your doctor how long you should wait between your doses of these drugs.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: drugs for diabetes (e.g., insulin, tolbutamide), nitrates (e.g., isosorbide, nitroglycerin), SSRI antidepressants (e.g., fluoxetine, fluvoxamine).Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, other migraine medications) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of those products.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.