methysergide - oral


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WARNING: When used for an extended time, methysergide has infrequently caused abnormal thickening of heart valves and of the lining of the lungs/abdomen. Therefore, methysergide should be used only when the headaches are frequent and severe. Patients must be under close medical supervision.

Tell your doctor immediately if you develop chest pain, difficulty breathing, backache, trouble urinating, unusual tiredness, numbness or tingling of the hands or feet, or fast heartbeat.

USES: This medication is used to prevent or decrease the pain/frequency of certain severe recurring headaches (vascular headaches such as migraine headaches and cluster headaches). Because of possible serious side effects, it is used after other treatments (e.g., beta blockers) have not worked.Methysergide is an ergot alkaloid. It is thought to work by narrowing blood vessels in the head, thereby reducing the throbbing effects of vascular headaches. Methysergide is not used to treat migraine attacks when they occur.

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