methylphenidate patch (Daytrana)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

ADHD Symptoms in Children

What is methylphenidate patch, and how does it work (mechanism of action)?

Methylphenidate is a medication used for treating attention deficit hyperactivity disorder (ADHD). It stimulates the central nervous system (CNS or brain) in a manner that is similar to amphetamines; however, its actions are milder than amphetamines. Amphetamines stimulate the brain by increasing the level of neurotransmitters, dopamine and norepinephrine, in the brain (neurotransmitters are chemicals produced by nerves that are released and attach to other nearby nerves as a means of communication among nerves). The exact mechanism of action of the drug in people with ADHD is unknown. Methylphenidate is the active ingredient in methylphenidate (Ritalin, Concerta), and also is available as pills and liquids. The FDA approved Methylphenidate patches in April 2006.

What brand names are available for methylphenidate patch?

Daytrana

Is methylphenidate patch available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for methylphenidate patch?

Yes

What are the side effects of methylphenidate patch?

Side effects of methylphenidate are decreased appetite, sleeplessness, allergic contact dermatitis, nausea, vomiting, weight loss, dizziness, abdominal pain, emotional instability, and anorexia.

Methylphenidate may be abused and it is a Schedule II controlled medication. Long-term abuse can cause tolerance, psychological dependence, abnormal behavior, and psychosis. Use cautiously in people with a history of drug or alcohol abuse.

Quick GuideADHD Symptoms in Children

ADHD Symptoms in Children

What is the dosage for methylphenidate patch?

The recommended dose for methylphenidate patches is to apply one 10 mg patch once daily for 9 hours for week 1, then increase to 15 mg patch for week 2, then increase to 20 mg patch for week 3, then increase to 30 mg patch for week 4 depending on response. The patch is applied to the hip area 2 hours before the effect is needed, and removed 9 hours after application. The dosing is for children aged 6 to 17.

Which drugs or supplements interact with methylphenidate patch?

Methylphenidate should not be combined with monoamine oxidase inhibitors (MAOIs) such as phenelzine (Nardil), selegiline (Zelapar, Emsam, and Eldepryl), tranylcypromine (Parnate), procarbazine (Matulane), rasagiline (Azilect), and isocarboxazid (Marplan) because of risks of hypertensive crisis. Use of methylphenidate and MAO inhibitors should be separated by at least 14 days.

Is methylphenidate patch safe to take if I'm pregnant or breastfeeding?

There are no adequate studies done on Methylphenidate to determine safe and effective use in pregnant women.

It is not known whether methylphenidate enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

What else should I know about methylphenidate patch?

What preparations of methylphenidate patch are available?

Patch: 10 mg, 15 mg, 20 mg, and 30 mg strengths, delivering doses over 9 hours.

How should I keep methylphenidate patch stored?

Store Methylphenidate patches between temperatures of 15 C and 30 C (59 F and 86 F). Do not store patches unpouched (outside of their container). Do not store patches in refrigerators or freezers. Once the sealed tray or outer pouch is opened, use contents within 2 months.

Medically reviewed by John Cunha, DO

REFERENCE: FDA Prescribing Information.

Last Editorial Review: 8/8/2017

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Reviewed on 8/8/2017
References
Medically reviewed by John Cunha, DO

REFERENCE: FDA Prescribing Information.

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