methyldopa/hydrochlorothiazide - oral (cont.)
DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: cisapride, dofetilide.If you are currently using either of these medications listed above, tell your doctor or pharmacist before starting methyldopa with hydrochlorothiazide.Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during and after treatment with methyldopa. In some cases a serious, possibly fatal drug interaction may occur. If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: digoxin, entacapone, iron products (e.g., ferrous sulfate), levodopa, amphetamines, quinidine, lithium, medication to lower blood sugar (e.g., glyburide, insulin), corticosteroids (e.g., hydrocortisone, prednisone), nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen).Before taking this medication, tell your doctor of any other blood pressure medications you are taking (e.g., beta blockers such as propranolol, calcium channel blockers such as nifedipine, ACE inhibitors such as lisinopril, diuretics such as furosemide).Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could cause drowsiness or increase your heart rate/blood pressure. Ask your pharmacist about the safe use of those products.Tell your doctor and pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine, phenobarbital), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., hydrocodone, codeine), psychiatric medications (e.g., chlorpromazine, risperidone, amitriptyline, trazadone).Caffeine may increase your blood pressure. Caffeine can be found in nonprescription diet medications, soft drinks, coffee and tea. Limit caffeine intake.This medication may interfere with certain laboratory tests (e.g., matching blood, parathyroid), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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