methocarbamol (Robaxin, Robaxin-750)

  • Pharmacy Author:
    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

What is the dosage for methocarbamol-oral?

Musculoskeletal pain in adults:

  • Initially, take three 500 mg tablets by mouth 4 times a day for first 48 to 72 hours, then take 2 tablets by mouth 4 times a day for the maintenance of spasms.
  • If using 750 mg tablets take 2 tablets by mouth 4 times a day for the first 48 to 72 hours, then take 1 tablet by mouth every 4 hours or take 2 tablets by mouth 3 times a day for the maintenance of spasms.
  • The dose for injections is 1 gram intravenously or intramuscularly every 8 hours with a maximum dose of 3 grams per day for 3 days.
    • If needed, the same course may be repeated after a 48 hour drug free interval.

Tetanus spasms:

  • Adults: Inject 1 to 2 grams intravenously every 6 hours as needed with a maximum dose of 24 grams per day.
  • Children: Inject 15 mg/kg intravenously every 6 hours as needed.
    • The total dose should not exceed 1.8 g/m2 for 3 consecutive days.

Which drugs or supplements interact with methocarbamol-oral?

Methocarbamol can increase sedation if taken with narcotic painkillers, alcohol, sedative or hypnotic medications, and other medications that depress the central nervous system. Loss of consciousness, troubled breathing, lowered heart rate, and in severe cases death or coma can also occur.

Medically Reviewed by a Doctor on 7/1/2016

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