methadone, Dolophine, Methadone HCl Intensol, Methadose, Methadose Sugar-Free

  • Pharmacy Author:
    Eni Williams, PharmD, PhD

    Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Is methadone liquid-oral safe to take if I'm pregnant or breastfeeding?

Safety during pregnancy has not been established. Methadone has been shown to cross the placenta, and it is found in cord blood, amniotic fluid and in the newborn urine. Children born to mothers who were taking methadone for a prolonged period may exhibit respiratory depression or withdrawal symptoms. Methadone enters breast milk, and this can cause sedation and respiratory depression in the breast feeding infant. The benefit to the mother of taking methadone while breast feeding should be weighed against the risks to the infant.

What else should I know about methadone liquid-oral?

What preparations of methadone liquid-oral are available?

  • Oral concentrate: 10 mg/mL;
  • Oral solution: 5 and 10 mg per teaspoon;
  • Oral tablet: 5 mg and 10 mg;
  • Soluble tablet, 40mg;
  • Solution for Injection 5 and 10 mg per teaspoon: 10 mg/mL.

How should I keep methadone liquid-oral stored?

Oral methadone and injection should be stored at room temperature between 15 C and 30 C (59 F and 86 F). Methadone injection also should be protected from light.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 1/21/2016

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