methadone (liquid oral) (cont.)
Eni Williams, PharmD, PhD
Eni Williams, PharmD, PhD
Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.
Medical and Pharmacy Editor:
HOW TO USE: Take this medication only by mouth. To prevent upset stomach, take with food or milk. Take this as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time without your doctor's approval. Also, if used for a long period of time at high doses, do not suddenly stop taking this without first consulting your doctor. When used for extended periods, this medication may not work as well and may require different dosing. Consult your doctor if the medication isn't working properly.
SIDE EFFECTS: May cause constipation, lightheadedness, dizziness, drowsiness, stomach upset, nausea, and flushing the first few days as your body adjusts to the medication. If these symptoms persist or become bothersome, inform your doctor. To minimize constipation, increase your intake of fiber, drink plenty of water, and exercise. Stool softeners may be helpful. Ask your doctor or pharmacist about stool softeners and laxatives. Notify your doctor if you develop: irregular heartbeat, anxiety, tremors, seizures. In the unlikely event you have a serious allergic reaction to this drug, seek medical attention immediately. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: stomach problems (e.g., colitis), substance abuse problems, uncorrected low mineral levels in the blood (e.g., potassium and magnesium), certain heart diseases (cardiac hypertrophy, cardiac conduction conditions--e.g., prolonged QT interval), any allergies. Use caution engaging in activities requiring alertness such as driving or using machinery. Alcoholic beverages may add to the effects of this medication causing dizziness or drowsiness. Ask your doctor or pharmacist about alcohol use. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and may affect the infant. Consult your doctor before breast-feeding.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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