methadone (Dolophine; Methadone HCl Intensol; Methadose; Methadose Sugar-Free)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Is methadone-oral tablet safe to take if I'm pregnant or breastfeeding?

Safety during pregnancy has not been established. Methadone has been shown to cross the placenta, and it is found in cord blood, amniotic fluid and in the newborn urine. Children born to mothers who were taking methadone for a prolonged period may exhibit respiratory depression or withdrawal symptoms.

Methadone enters breast milk, and this can cause sedation and respiratory depression in the breastfeeding infant. The benefit to the mother of taking methadone while breast feeding should be weighed against the risks to the infant.

What else should I know about methadone-oral tablet?

What preparations of methadone-oral tablet are available?

  • Oral concentrate: 10 mg/mL
  • Oral solution: 5 and 10 mg per teaspoon
  • Oral tablet: 5 mg and 10 mg
  • Soluble tablet, 40mg
  • Solution for Injection 5 and 10 mg per teaspoon: 10 mg/mL

How should I keep methadone-oral tablet stored?

Oral methadone and injection should be stored at room temperature between 15 C and 30 C (59 F and 86 F). Methadone injection also should be protected from light.

Medically reviewed by John P. Cunha, DO, FACOEP

REFERENCE:

FDA.gov Prescribing Information.

Medically Reviewed by a Doctor on 5/12/2017

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