methadone (Dolophine; Methadone HCl Intensol; Methadose; Methadose Sugar-Free)

Pharmacy Author:
Medical and Pharmacy Editor:


BRAND NAME: Dolophine; Methadone HCl Intensol; Methadose; Methadose Sugar-Free

DRUG CLASS AND MECHANISM: Methadone is a strong, synthetic (man-made) narcotic that acts on the central nervous system (brain) in a manner similar to other narcotics. It is used in the management of narcotic addiction and for pain control. Methadone was first approved by the Food and Drug Administration on August 13 1947.




  • Oral concentrate: 10 mg/mL
  • Oral solution: 5 and 10 mg per teaspoon
  • Oral tablet: 5 mg and 10 mg
  • Soluble tablet, 40mg
  • Solution for Injection 5 and 10 mg per teaspoon: 10 mg/mL

STORAGE: Oral methadone and injection should be stored at room temperature between 15 C and 30 C (59 F and 86 F). Methadone injection also should be protected from light.

PRESCRIBED FOR: Methadone is used for the treatment of moderate to severe pain when non-narcotic pain medications have failed. The extended release methadone tablets should be reserved for severe and continuous pain that requires long-term pain treatment after a failed trial of non-narcotic medications and should be avoided in individuals requiring as-needed pain control.

Medically Reviewed by a Doctor on 4/16/2014

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index