methadone - injection, Dolophine
GENERIC NAME: METHADONE - INJECTION (METH-a-done)
BRAND NAME(S): Dolophine
WARNING: Methadone has caused very serious (possibly fatal) breathing and heart rhythm problems (QT prolongation in the EKG, torsades de pointes). These problems are more likely to occur when this medication is first started or when the dose is increased. Breathing problems may occur a while after you receive the dose (for example, more than 8 hours later). Carefully follow your doctor's directions on how to use the medication. Even if this medication is not working well, do not increase your dose or use this medication more often than prescribed without first consulting your doctor. It may sometimes take 3 to 5 days before you get the full benefit of pain relief from this medication. Seek immediate medical attention if you develop symptoms of breathing and heart rhythm problems, such as slow/shallow breathing, fast/irregular heartbeat, severe dizziness, or fainting.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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